![]() SMMCI is seen in both deciduous and permanent dentition and is characterized by the presence of symmetric maxillary central incisor, the absence of labial frenum and incisive papilla with narrow nose. The etiology of SMMCI is believed to be unknown events occurring between the 35 th and 38 th days in utero involving midline structures of the head including the cranial bones, the maxilla, its dentition specifically central incisor, the nasal airways and sometimes the brain (holoprosencephaly ) with other midline structures of the body. (1997) originally named this syndrome as “Solitary median maxillary central incisor, short stature, choanal atresia/midnasal stenosis syndrome”, it is now shortened to “Solitary median maxillary central incisor syndrome” or SMMCI syndrome. found a frequent association of short stature and solitary maxillary incisor and named the condition “monosuperoincisivodontic dwarfism.” Since then, multiple cases of SMMCI with or without systemic involvement have been reported in the literature. The presence of solitary symmetrical central incisor was first reported by Scott. ![]() SMMCI is characterized by a symmetrical single maxillary central incisor tooth located exactly in the midline of the maxillary alveolus. SMMCI has an occurrence rate of 1:50,000 live births with a higher incidence in women. Solitary median maxillary central incisor (SMMCI) syndrome is a rare developmental disorder affecting the maxillary central incisor tooth germs. ![]()
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